EvoPrinter - Introduction
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achaete-scute homolog-1 CNS Enhancer
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The following slides (1-7) depict key steps in the generation of an EvoPrint and EvoDifference print of the mammalian ash-1 (Mash-1) CNS enhancer (see references below).

Select images to enlarge. Arrows will allow you to scroll through all 7 examples.
Screenshot of window that shows a human BLAT search query

1.
2.5 kb of mouse Mash-1 upstream DNA loaded into the human BLAT search window
Screenshot of window that shows human BLAT search results

2.
Alignment scores of Human test-species BLAT search results
Screenshot of window that shows human BLAT alignment

3.
2.5 kb of mouse Mash-1 upstream DNA loaded into the human BLAT search window
Screenshot of Evoprint window that shows mouse alignment outputs from 6 vertebrate species

4.
EvoPrinter input windows showing mouse alignment outputs from six vertebrate species
Screenshot of Evoprint analysis window that shows conserved nucleotides or amino acids in 6 vertebrate species

5.
Mash-1 CNS enhancer region EvoPrint loaded into the human BLAT search window
Screenshot of Evoprint window that shows conserved sequences from 6 vertebrate species

6.
Input windows configured to generate a Xenopus tropicalis EvoDifference print
Screenshot of Evoprint window that shows nucleotides or amino acids conserved in all species analyzed and sequences common to all species except Xenopus

7.
Input windows configured to generate a Xenopus tropicalis EvoDifference print

References

Verma-Kurvari, S., Savage, T., Gowan, K. & Johnson J. E. (1996). Lineage-specific
regulation of the neural differentiation gene MASH1. Dev. Biol. 180, 605-17.

Verma-Kurvari, S., Savage, T., Smith, D. & Johnson J. E. (1998). Multiple elements
regulate Mash1 expression in the developing CNS. Dev. Biol. 197, 106-16